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1

Immune response profile of caruncular and trophoblast cell lines infected by high- (Nc-Spain7) and low-virulence (Nc-Spain1H) isolates of Neospora caninum

Jiménez-Pelayo, Laura, García-Sánchez, Marta, Regidor-Cerrillo, Javier, Horcajo, Pilar, Collantes-Fernández, Esther, Gómez-Bautista, Mercedes, Hambruch, Nina, Pfarrer, Christiane, Ortega-Mora, Luis Mi

Journal:

Parasites & Vectors

Year:

2019

File:

PDF, 1.16 MB

2019

2

Sternal bone marrow derived equine multipotent mesenchymal stromal cells (MSCs): investigations considering the sampling site and the use of different culture media

Eydt, Carina, Geburek, Florian, Schröck, Carmen, Hambruch, Nina, Rohn, Karl, Pfarrer, Christiane, Staszyk, Carsten

Journal:

Veterinary Medicine and Science

Year:

2016

Language:

english

File:

PDF, 485 KB

english, 2016

3

A Novel Pex14 Protein-interacting Site of Human Pex5 Is Critical for Matrix Protein Import into Peroxisomes

Neuhaus, A., Kooshapur, H., Wolf, J., Meyer, N. H., Madl, T., Saidowsky, J., Hambruch, E., Lazam, A., Jung, M., Sattler, M., Schliebs, W., Erdmann, R.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.94 MB

english, 2014

4

Changes in endometrial ezrin and cytokeratin 18 expression during bovine implantation and in caruncular endometrial spheroids in vitro

Haeger, J.-D., Hambruch, N., Dantzer, V., Hoelker, M., Schellander, K., Klisch, K., Pfarrer, C.

Journal:

Year:

2015

Language:

english

File:

PDF, 19.50 MB

english, 2015

5

Histological evaluation of equine cadaver skin cores dependent on needle type and skin preparation method to investigate intramuscular injection complications in horses

Puschmann, Tobias, Haeger, Jan-Dirk, Hambruch, Nina, Rohn, Karl, Pfarrer, Christiane, Ohnesorge, Bernhard

Journal:

Journal of Equine Veterinary Science

Year:

2016

Language:

english

File:

PDF, 1.08 MB

english, 2016

6

Seminal plasma modulates the immune-cytokine network in the porcine uterine tissue and pre-ovulatory follicles

Waberski, Dagmar, Schäfer, Jana, Bölling, Alexandra, Scheld, Manon, Henning, Heiko, Hambruch, Nina, Schuberth, Hans-Joachim, Pfarrer, Christiane, Wrenzycki, Christine, Hunter, Ronald H. F., Rosenfeld,

Journal:

Year:

2018

Language:

english

File:

PDF, 6.09 MB

english, 2018

7

99 NOVEL FXR AGONISTS WITH POTENT LIPID LOWERING, INSULIN SENSITISING, ANTI-INFLAMMATORY AND ANTI-FIBROTISATION EFFECTS IN MOUSE MODELS OF METABOLIC SYNDROME AND NASH

C. Kremoser, E. Hambruch, U. Deuschle, O. Kinzel, M. Burnet, H. Yoneyama

Journal:

Journal of Hepatology

Year:

2011

Language:

english

File:

PDF, 32 KB

english, 2011

8

Fxr Agonism by Gs-9674 Decreases Steatosis and Fibrosis in a Murine Model of Nash

Liles, J.T., Karnik, S., Hambruch, E., Kremoser, C., Birkel, M., Watkins, W.J., Tumas, D., Breckenridge, D., French, D.

Journal:

Journal of Hepatology

Year:

2016

Language:

english

File:

PDF, 55 KB

english, 2016

9

Establishment and functional characterization of a murine primary Sertoli cell line deficient of connexin43

Gerber, Jonathan, Rode, Kristina, Hambruch, Nina, Langeheine, Marion, Schnepel, Nadine, Brehm, Ralph

Journal:

Cell and Tissue Research

Year:

2020

File:

PDF, 1.02 MB

2020

10

The near term shift of syndecan protein to an epithelial localization suggests an involvement in placental maturation and release of bovine fetal membranes

Hambruch, Nina, Kumstel, Simone, Dantzer, Vibeke, Pfarrer, Christiane

Journal:

Year:

2015

Language:

english

File:

PDF, 373 KB

english, 2015

11

1244 FXR AGONISTS PREVENT STEATOSIS, HEPATOCYTE DEATH AND PROGRESSION OF NASH TOWARDS HCC IN A HYPOINSULINAEMIC MOUSE MODEL OF PROGRESSIVE LIVER DISEASE

Kremoser, C., Hambruch, E., Deuschle, U., Yoneyama, H.

Journal:

Journal of Hepatology

Year:

2012

Language:

english

File:

PDF, 53 KB

english, 2012

12

Recombinant bovine S100A8 and A9 enhance IL-1β secretion of interferon-gamma primed monocytes

Koy, Mirja, Hambruch, Nina, Hussen, Jamal, Pfarrer, Christiane, Seyfert, Hans-Martin, Schuberth, Hans-Joachim

Journal:

Veterinary Immunology and Immunopathology

Year:

2013

Language:

english

File:

PDF, 1.34 MB

english, 2013

13

P-glycoprotein is functionally expressed in the placenta-derived bovine caruncular epithelial cell line 1 (BCEC-1)

B. Waterkotte, N. Hambruch, B. Döring, J. Geyer, H.-R. Tinneberg, C. Pfarrer

Journal:

Year:

2011

Language:

english

File:

PDF, 641 KB

english, 2011

14

Discussion

Kremoser, C., Hambruch, E., Deuschle, U., Yoneyama, H.

Journal:

Journal of Vascular Surgery

Year:

2007

Language:

english

File:

PDF, 37 KB

english, 2007

15

An Acute-phase Protein as a Regulator of Sperm Survival in the Bovine Oviduct: Alpha 1-acid-glycoprotein Impairs Neutrophil Phagocytosis of Sperm In Vitro

LIU, Jinghui, MAREY, Mohamed A., KOWSAR, Rasoul, HAMBRUCH, Nina, SHIMIZU, Takashi, HANEDA, Shingo, MATSUI, Motozumi, SASAKI, Motoki, HAYAKAWA, Hiroyuki, PFARRER, Christiane, MIYAMOTO, Akio

Journal:

Journal of Reproduction and Development

Year:

2014

Language:

english

File:

PDF, 1.54 MB

english, 2014

16

Local immune system in oviduct physiology and pathophysiology: attack or tolerance?

Marey, M.A., Yousef, M.S., Kowsar, R., Hambruch, N., Shimizu, T., Pfarrer, C., Miyamoto, A.

Journal:

Domestic Animal Endocrinology

Year:

2016

Language:

english

File:

PDF, 2.08 MB

english, 2016

17

The FXR agonist GS-9674 reduces fibrosis and portal hypertension in a rat model of NASH

Schwabl, P., Budas, G., Hambruch, E., Supper, P., Burnet, M., Liles, J., Sullivan, T., Huntzicker, E., Birkel, M., French, D., Tumas, D., Peck-Radosavljevic, M., Watkins, W., Trauner, M., Breckenridge

Journal:

Journal of Hepatology

Year:

2018

Language:

english

File:

PDF, 89 KB

english, 2018

18

FRI-303-How to develop a differentiated FXR agonist: GS-9674 shows a reduced side effect profile in mice, monkeys amd human phase 1 studies compared to its predecessor Px-102

Hambruch, Eva, Hollenback, David, Liles, John, Kinzel, Olaf, Birkel, Manfred, Fink, Gero, French, Dorothy, Gege, Christian, Hornberger, Martin, Watkins, William, Kremoser, Claus

Journal:

Journal of Hepatology

Year:

2019

File:

PDF, 1.32 MB

2019

19

The Non-Steroidal Fxr Agonist Gs-9674 Reduces Liver Fibrosis and Ameliorates Portal Hypertension in a Rat Nash Model

Schwabl, P., Hambruch, E., Supper, P., Burnet, M., Peck-Radosavljevic, M., Reiberger, T., Kremoser, C., Trauner, M.

Journal:

Journal of Hepatology

Year:

2016

Language:

english

File:

PDF, 63 KB

english, 2016

20

Differential susceptibility of bovine caruncular and trophoblast cell lines to infection with high and low virulence isolates of Neospora caninum

Jiménez-Pelayo, Laura, García-Sánchez, Marta, Regidor-Cerrillo, Javier, Horcajo, Pilar, Collantes-Fernández, Esther, Gómez-Bautista, Mercedes, Hambruch, Nina, Pfarrer, Christiane, Ortega-Mora, Luis Mi

Journal:

Parasites & Vectors

Year:

2017

Language:

english

File:

PDF, 3.02 MB

english, 2017

21

From Mice to Men – Changes in FGF15/19 Expression and Bile Acid Levels as Sensitive Markers of Pharmacological FXR Activation; Results from Human Phase I and Animal Studies Using the Potent and Selective FXR Agonist Px-102

Hambruch, E., Krol, H., Perović-Ottstadt, S., Hornberger, M., Steeneck, C., Kinzel, O., Deuschle, U., Birkel, M., Kremoser, C.

Journal:

Journal of Hepatology

Year:

2016

Language:

english

File:

PDF, 102 KB

english, 2016

22

FRI-303-How to develop a differentiated FXR agonist: GS-9674 shows a reduced side effect profile in mice, monkeys amd human phase 1 studies compared to its predecessor Px-102

Hambruch, Eva, Hollenback, David, Liles, John, Kinzel, Olaf, Birkel, Manfred, Fink, Gero, French, Dorothy, Gege, Christian, Hornberger, Martin, Watkins, William, Kremoser, Claus

Journal:

Journal of Hepatology

Year:

2019

Language:

english

File:

PDF, 1.32 MB

english, 2019

23

Isolation and characterization of multipotent mesenchymal stromal cells from the gingiva and the periodontal ligament of the horse

Niels Mensing, Hagen Gasse, Nina Hambruch, Jan-Dirk Haeger, Christiane Pfarrer, Carsten Staszyk

Journal:

BMC Veterinary Research

Year:

2011

Language:

english

File:

PDF, 13.26 MB

english, 2011

24

Variation in Macrophage Migration Inhibitory Factor [MIF] immunoreactivity during bovine gestation

L. Paulesu, C. Pfarrer, R. Romagnoli, F. Ietta, H. Callesen, N. Hambruch, V. Dantzer

Journal:

Year:

2012

Language:

english

File:

PDF, 1.85 MB

english, 2012

25

The nuclear bile acid receptor FXR controls the liver derived tumor suppressor histidine-rich glycoprotein

Deuschle, Ulrich, Birkel, Manfred, Hambruch, Eva, Hornberger, Martin, Kinzel, Olaf, Perović-Ottstadt, Sanja, Schulz, Andreas, Hahn, Ulrike, Burnet, Michael, Kremoser, Claus

Journal:

International Journal of Cancer

Year:

2015

Language:

english

File:

PDF, 595 KB

english, 2015

26

LXR inverse agonists inhibit de novo lipogenesis and reduce intestinal lipid and cholesterol absorption in a NAFLD mouse model

Kremoser, C., Deuschle, U., Gege, C., Kinzel, O., Krol, H.D., Albers, M., Birkel, M., Hambruch, E.

Journal:

Journal of Hepatology

Year:

2018

Language:

english

File:

PDF, 179 KB

english, 2018

27

EGF stimulates proliferation in the bovine placental trophoblast cell line F3 via Ras and MAPK

N. Hambruch, J.-D. Haeger, M. Dilly, C. Pfarrer

Journal:

Year:

2010

Language:

english

File:

PDF, 1.37 MB

english, 2010

28

Evidence for a novel, local acute-phase response in the bovine oviduct: Progesterone and lipopolysaccharide up-regulate alpha 1-acid-glycoprotein expression in epithelial cells in vitro

Kowsar, R., Hambruch, N., Marey, M.A., Liu, J., Shimizu, T., Pfarrer, C., Miyamoto, A.

Journal:

Molecular Reproduction and Development

Year:

2014

Language:

english

File:

PDF, 1.11 MB

english, 2014

29

Transcriptome modulation of bovine trophoblast cells in vitro by Neospora caninum

Horcajo, Pilar, Jiménez-Pelayo, Laura, García-Sánchez, Marta, Regidor-Cerrillo, Javier, Collantes-Fernández, Esther, Rozas, Daniel, Hambruch, Nina, Pfarrer, Christiane, Ortega-Mora, Luis Miguel

Journal:

International Journal for Parasitology

Year:

2017

Language:

english

File:

PDF, 2.12 MB

english, 2017

30

Placental cellular products affect the expression of extracellular matrix (ECM) components and corresponding matrix metalloproteinases (MMP) in bovine placental fibroblasts and trophoblasts in vitro

Hambruch, Nina, Koehlbrandt, Joergen, Pfarrer, Christiane

Journal:

Year:

2014

Language:

english

File:

PDF, 43 KB

english, 2014

31

Novel substituted isoxazole FXR agonists with cyclopropyl, hydroxycyclobutyl and hydroxyazetidinyl linkers: Understanding and improving key determinants of pharmacological properties

Kinzel, Olaf, Steeneck, Christoph, Schlüter, Thomas, Schulz, Andreas, Gege, Christian, Hahn, Ulrike, Hambruch, Eva, Hornberger, Martin, Spalwisz, Adriana, Frick, Katharina, Perović-Ottstadt, Sanja, De

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 869 KB

english, 2016

32

G18 : The FXR agonist PX20606 reduces liver damage, fibrosis and portal hypertension in cirrhotic rats

Schwabl, P., Hambruch, E., Payer, B.A., Schubert, T.L., Strobel, B., Fida, S., Wagner, M., Garnys, L., Trauner, M., Peck-Radosavljevic, M., Kremoser, C., Reiberger, T.

Journal:

Journal of Hepatology

Year:

2015

Language:

english

File:

PDF, 41 KB

english, 2015

33

Synthesis and pharmacological validation of a novel series of non-steroidal FXR agonists

Ulrich Abel, Thomas Schlüter, Andreas Schulz, Eva Hambruch, Christoph Steeneck, Martin Hornberger, Thomas Hoffmann, Sanja Perović-Ottstadt, Olaf Kinzel, Michael Burnet, Ulrich Deuschle, Claus Kremoser

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 707 KB

english, 2010

34

Membrane Association of the Cycling Peroxisome Import Receptor Pex5p

Kerssen, D., Hambruch, E., Klaas, W., Platta, H. W., de Kruijff, B., Erdmann, R., Kunau, W.-H., Schliebs, W.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 1.16 MB

english, 2006

35

Characterization of a Peptide that Specifically Blocks the Ras Binding Domain of p75

Silvia Egert, Heike Piechura, Nina Hambruch, Martin Feigel, Andrea Blöchl

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2007

Language:

english

File:

PDF, 357 KB

english, 2007

36

Epidermal growth factor (EGF) induces motility and upregulates MMP-9 and TIMP-1 in bovine trophoblast cells

M. Dilly, N. Hambruch, J.-D. Haeger, C. Pfarrer

Journal:

Molecular Reproduction and Development

Year:

2010

Language:

english

File:

PDF, 202 KB

english, 2010

37

The bovine placenta in vivo and in vitro

Haeger, J.-D., Hambruch, N., Pfarrer, C.

Journal:

Year:

2016

Language:

english

File:

PDF, 367 KB

english, 2016

38

Synthetic Farnesoid X Receptor Agonists Induce High-Density Lipoprotein-Mediated Transhepatic Cholesterol Efflux in Mice and Monkeys and Prevent Atherosclerosis in Cholesteryl Ester Transfer Protein Transgenic Low-Density Lipoprotein Receptor (-/-) Mice

Hambruch, E., Miyazaki-Anzai, S., Hahn, U., Matysik, S., Boettcher, A., Perovic-Ottstadt, S., Schluter, T., Kinzel, O., Krol, H. D., Deuschle, U., Burnet, M., Levi, M., Schmitz, G., Miyazaki, M., Krem

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2012

Language:

english

File:

PDF, 2.12 MB

english, 2012

39

Ferdinand von Richthofens Vorlesungen über allgemeine Siedlungs- und Verkehrsgeographieby Otto Schlüter

Review by: Paul Hambruch

Journal:

Zeitschrift für Ethnologie

Year:

1909

Language:

german

File:

PDF, 316 KB

german, 1909

40

Regulation of Innate Immune Function in Bovine Oviduct Epithelial Cells in Culture: The Homeostatic Role of Epithelial Cells in Balancing Th1/Th2 Response

KOWSAR, Rasoul, HAMBRUCH, Nina, LIU, Jinghui, SHIMIZU, Takashi, PFARRER, Christiane, MIYAMOTO, Akio

Journal:

Journal of Reproduction and Development

Year:

2013

Language:

english

File:

PDF, 5.29 MB

english, 2013

41

Influence of intra-uterine seminal plasma infusion on gene expression of transcripts associated with local immune reactions in estrous pigs

Nitz, J., Bölling, A., Henning, H., Hambruch, N., Schuberth, H.J., Pfarrer, C., Wrenzycki, C., Hunter, R.H.F., Waberski, D.

Journal:

Reproductive Biology

Year:

2013

Language:

english

File:

PDF, 71 KB

english, 2013

42

Galectin fingerprinting detects differences in expression profiles between bovine endometrium and placentomes as well as early and late gestational stages

R. Froehlich, N. Hambruch, J.-D. Haeger, M. Dilly, H. Kaltner, H.-J. Gabius, C. Pfarrer

Journal:

Year:

2012

Language:

english

File:

PDF, 1.82 MB

english, 2012

43

The FXR agonist PX20606 ameliorates portal hypertension by targeting vascular remodelling and sinusoidal dysfunction

Schwabl, Philipp, Hambruch, Eva, Seeland, Berit A., Hayden, Hubert, Wagner, Michael, Garnys, Lukas, Strobel, Bastian, Schubert, Tim-Lukas, Riedl, Florian, Mitteregger, Dieter, Burnet, Michael, Starlin

Journal:

Journal of Hepatology

Year:

2017

Language:

english

File:

PDF, 2.63 MB

english, 2017

44

Expression of matrix metalloproteinase (MMP)-2, MMP-14 and tissue inhibitor of matrix metalloproteinase (TIMP)-2 during bovine placentation and at term with or without placental retention

M. Dilly, N. Hambruch, S. Shenavai, G. Schuler, R. Froehlich, J.-D. Haeger, G.R. Ozalp, C. Pfarrer

Journal:

Year:

2011

Language:

english

File:

PDF, 3.08 MB

english, 2011

45

Formation of Bovine Placental Trophoblast Spheroids

Haeger, J.-D., Hambruch, N., Dilly, M., Froehlich, R., Pfarrer, C.

Journal:

Cells Tissues Organs

Year:

2011

Language:

english

File:

PDF, 1.07 MB

english, 2011

46

Bovine placentomal heparanase and syndecan expression is related to placental maturation

Hambruch, N., Kumstel, S., Haeger, J.-D., Pfarrer, C.

Journal:

Year:

2017

Language:

english

File:

PDF, 3.50 MB

english, 2017

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